منابع مشابه
SnapShot: The Bacterial Cytoskeleton
Most bacteria and archaea contain filamentous proteins and filament systems that are collectively known as the bacterial cytoskeleton, though not all of them are cytoskeletal, affect cell shape, or maintain intracellular organization. To view this SnapShot, open or download the PDF.
متن کاملThe Bacterial Actin Cytoskeleton
M icrobial shape, long used as a taxonomic criterion, is genetically determined. But how DNA sequence information is translated into morphology is a seminal question still without a complete answer for any microorganism. Recently, however, when investigators discovered that actin-like proteins are involved in determining bacterial cell shape, they revolutionized the field. This insight provides...
متن کاملThe bacterial actin-like cytoskeleton.
Recent advances have shown conclusively that bacterial cells possess distant but true homologues of actin (MreB, ParM, and the recently uncovered MamK protein). Despite weak amino acid sequence similarity, MreB and ParM exhibit high structural homology to actin. Just like F-actin in eukaryotes, MreB and ParM assemble into highly dynamic filamentous structures in vivo and in vitro. MreB-like pro...
متن کاملA dynamic bacterial cytoskeleton.
Actin and tubulin are the major components of the cytoskeleton that pervades the cytoplasm of all eukaryotic cells. These proteins were traditionally thought not to be present in prokaryotes, but structural and functional homologues of tubulin (FtsZ) and actin (MreB) are now known to be present virtually throughout the eubacteria and in some archae. FtsZ protein is a key player in cell division...
متن کاملBacterial toxins modifying the actin cytoskeleton.
Numerous bacterial toxins recognize the actin cytoskeleton as a target. The clostridial binary toxins (Iota and C2 families) ADP-ribosylate the actin monomers causing the dissociation of the actin filaments. The large clostridial toxins from Clostridium difficile, Clostridium sordellii and Clostridium novyi inactivate, by glucosylation, proteins from the Rho family that regulate actin polymeriz...
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ژورنال
عنوان ژورنال: CBE—Life Sciences Education
سال: 2006
ISSN: 1931-7913
DOI: 10.1187/cbe.06-09-0188